Passive versus Active Tumor Targeting Using RGD- and NGR-Modified Polymeric Nanomedicines
نویسندگان
چکیده
منابع مشابه
Targeting tumor microenvironment: crossing tumor interstitial fluid by multifunctional nanomedicines
INTRODUCTION The genesis of cancer appears to be a complex matter, which is not simply based upon few genetic abnormalities/alteration. In fact, irregular microvasculature and aberrant interstitium of solid tumors impose significant pathophysiologic barrier functions against cancer treatment modalities, hence novel strategies should holistically target bioelements of tumor microenvironment (TME...
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ژورنال
عنوان ژورنال: Nano Letters
سال: 2014
ISSN: 1530-6984,1530-6992
DOI: 10.1021/nl404391r